Transcription profiling by array of human transiliac bone biopsies from pre and post surgery to investigate the molecular pathology of bone in hyperparathyroidism

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E-MEXP-847

Homo sapiens

14 Downloadable Samples

Affymetrix Human Genome U133A Array (hgu133a)

Submitter Supplied Information

Description

We analyzed mRNAs in transiliacal bone biopsies from 7 patients with primary hyperparathyroidism using Affymetrix HG-U133A Gene Chips Similar analyses of the global transcriptional activity were repeated in a second bone biopsy from the same patient taken one year after surgery and reversal of disease parameters.

PubMed ID

17227961

Publication Title

Abnormal muscle and hematopoietic gene expression may be important for clinical morbidity in primary hyperparathyroidism.

Total Samples

Submitter’s Institution

Department of Endocrinology, Odense University Hospital, Medical Biochemistry, University of Oslo, Dept. of Clinical Chemistry, Ullevaal University Hospital, University of Oslo, Department of Medical Biochemistry

Authors

Reppe S, Stilgren L, Abrahamsen B, Olstad OK, Cero F, Brixen K, Nissen-Meyer LS, Gautvik KM

Source Repository

ArrayExpress

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