Expression data of LPS-stimulated macrophages from wild-type, MyD88-/- and TRIF-/- mice.

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GSE14890

Mus musculus

9 Downloadable Samples

Affymetrix Mouse Expression 430A Array (moe430a)

Submitter Supplied Information

Description

Lipopolysaccharide (LPS), a Toll-like receptor (TLR) 4 ligand, activates intracellular signaling via adaptors, MyD88 and TRIF, leading to the expression of various genes including proinflammatory cytokines.

PubMed ID

19322177

Publication Title

Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay.

Total Samples

Submitter’s Institution

Kyoto University

Authors

Matsushita K, Takeuchi O, Standley DM, Kumagai Y, Kawagoe T, Miyake T, Satoh T, Kato H, Tsujimura T, Nakamura H, Akira S

Source Repository

Gene Expression Omnibus (GEO)

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