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Accession IconGSE29677

Effect of prenatal exposure to nicotine on kidney structure and gene expression in rats

Organism Icon Rattus norvegicus
Sample Icon 4 Downloadable Samples
Technology Badge Icon Affymetrix Rat Expression 230A Array (rae230a)

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Here, we investigated whether prenatal exposure to nicotine alters kidney glomerular mass and genome-wide gene expression profiles in two genetically distant strains of rats, namely spontaneously hypertensive rats (SHR) and Brown Norway (BN) rats. Nicotine or saline were administered to BN and SHR dams via osmotic pumps throughout gestation. Kidneys from 9-week-old male offspring were studied.
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