GSE36220Transcriptome study of hepatocytes isolated from transgenic mice expressing HCV core.
Mus musculus
12 Downloadable Samples
Affymetrix Mouse Gene 1.0 ST Array (mogene10st)Submitter Supplied Information
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Hepatitis C Virus (HCV) core protein plays a major role in HCV mediated liver pathologies. We have previously reported that HCV core variants isolated from tumoral (T) and non-tumoral (NT) livers were capable to alleviate Smad transcriptional activity and to shift TGF- responses from tumor suppressor effects to tumor promotion.
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