Genes regulated by the gamma secretase inhibitor in WT and Ikaros deficient DN3 cells

Build and Download Custom Datasets

refine.bio helps you build ready-to-use datasets with normalized transcriptome data from all of the world’s genetic databases.

GSE46091

Mus musculus

8 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

Lineage-negative thymocytes were cultured on OP9-DL1 stromal cells for 16h in the presence of DMSO or the gamma secretase inhibitor MRK-003. DN3 cells cells were then sorted and their transcriptome analyzed.

PubMed ID

24643801

Publication Title

The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells.

Total Samples

Submitter’s Institution

IGBMC

Authors

Geimer Le Lay AS, Oravecz A, Mastio J, Jung C, Marchal P, Ebel C, Dembélé D, Jost B, Le Gras S, Thibault C, Borggrefe T, Kastner P, Chan S

Source Repository

Gene Expression Omnibus (GEO)

No rows found