github link
Accession IconGSE46311

Gene expression analysis of growth hormone producing somatotroph pituitary adenomas

Organism Icon Homo sapiens
Sample Icon 16 Downloadable Samples
Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description
The epithelial marker E-cadherin plays a crucial role in epithelial mesenchymal transition (EMT). Decreased protein content in somatotroph adenomas has been associated with increased tumor size, invasion, and poor response to somatostatin analog (SA) treatment, but the potential mechanisms of EMT progression in these adenomas are lacking. Adenomas from sixteen acromegalic patients, eight with high (tertile 3)and eight with low (tertile 1) expression of E-cadherin where four adenomas treated with SA in each group, were screened for expressional candidate genes using Affymetrix human Gene Plus 2.0 Arrays. Analyses were performed to identify EMT-related transcripts.
PubMed ID
No associated PubMed ID
Publication Title
No associated publication
Total Samples
16
Submitter’s Institution
Authors
No associated authors

Samples

Show of 0 Total Samples
Filter
Add/Remove
Accession Code
Title
Sex
Age
Treatment
Processing Information
Additional Metadata
No rows found
Loading...