Gene expression analysis of B16-F1 melanoma tumors established in WT and Stat2KO mice

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GSE56792

Mus musculus

6 Downloadable Samples

Affymetrix Mouse Gene 2.0 ST Array (mogene20st)

Submitter Supplied Information

Description

STAT2 is an essential transcription factor in type I interferon (IFN) signaling. STAT2 mediates the antigrowth and apoptotic effects of IFN as demonstrated in cell lines thus leading to the hypothesis that STAT2 has tumor suppressor function.

PubMed ID

24895110

Publication Title

Host STAT2/type I interferon axis controls tumor growth.

Total Samples

Submitter’s Institution

Temple University

Authors

Yue C, Xu J, Tan Estioko MD, Kotredes KP, Lopez-Otalora Y, Hilliard BA, Baker DP, Gallucci S, Gamero AM

Source Repository

Gene Expression Omnibus (GEO)

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