Global Analysis of Post-transcriptional Gene Expression in Arsenite-treated Human BJ Fibroblasts

Arsenic is a potent environmental toxin and a cause of numerous health problems. Most studies have assumed that arsenic-induced changes in mRNA levels result from effects on gene transcription. The influence of arsenic on post-transcriptional regulation, another important locus of gene expression control, has remained largely unexplored.

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Qiu LQ, Abey S, Harris S, Shah R, Gerrish KE, Blackshear PJ