Effect of TGF- on gene expression of human prostate cancer cells PC-3

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GSE58698

Homo sapiens

2 Downloadable Samples

Affymetrix Human Genome U133A Array (hgu133a)

Submitter Supplied Information

Description

Transforming growth factor- (TGF-) is a key factor for the development of prostate cancer metastases in bone. In breast cancer and melanoma, studies have shown how TGF- regulates gene expression to allow cancer cells to adapt to the bone microenvironment.

PubMed ID

25982816

Publication Title

The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone.

Total Samples

Submitter’s Institution

Indiana University

Authors

Fournier PG, Juárez P, Jiang G, Clines GA, Niewolna M, Kim HS, Walton HW, Peng XH, Liu Y, Mohammad KS, Wells CD, Chirgwin JM, Guise TA

Source Repository

Gene Expression Omnibus (GEO)

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