Characterization of chemokine and chemokine receptor expression during Pneumocystis infection in healthy and immunodeficient mice (part 1)

For both CD4 and micropajfe cell types, upregulated genes were primarily related to immune activation and proliferation, while down-regulated genes represented more diverse processes, including cell membranes, vasculature development, cell adhesion, and lipid-related metabolic processes.

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Bishop LR, Lionakis MS, Sassi M, Murphy PM, Hu X, Huang da W, Sherman B, Qiu J, Yang J, Lempicki RA, Kovacs JA