Transcriptome alterations induced by steroid receptors agonists in primary neurons and astrocytes

We utilized whole-genome microarrays (Illumina Mouse WG-6) to measure changes in mRNA abundance levels induced by steroid hormones in primary neurons and astrocytes. To stimulate gene expression we treated neuronal and astroglial cultures with glucocorticoid receptor agonist (dexamethasone), mineralocorticoid (aldosterone), progesterone (progesterone), androgen (5-dihydrotestosterone) and estrogen 2 (-estradiol).

48