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Accession IconSRP111379

Quantitative analysis of WT, Dnmt3a-/-, Dnmt3b-/- and Tet1-/- J1 ES cell transcriptomes

Organism Icon Mus musculus
Sample Icon 8 Downloadable Samples
Technology Badge IconNextSeq 500

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Description
In order to figure out the roles of Dnmt3 and Tet1 in gene regulation, we assessed global gene expression changes in Dnmt3aKO, Dnmt3bKO and Tet1KO ES cells. Overall design: mRNA profiles of WT, Dnmt3a-/- and Dnmt3b-/- ES cells; WT and Tet1-/- ES cells were generated by deep sequencing, in replicate, using Illumina HiSeq sequencing systems.
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8
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