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accession-icon GSE98490
Identification of GRF9 early responding genes using an estradiol-inducible overexpression (XVE) system.
  • organism-icon Arabidopsis thaliana
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

The aim of the experiment was to identify genes rapidly responding at their expression level to enhanced expression of the transcription factor GRF9.

Publication Title

GROWTH-REGULATING FACTOR 9 negatively regulates arabidopsis leaf growth by controlling ORG3 and restricting cell proliferation in leaf primordia.

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE38573
Expression data from cerebrum in a spontaneous mutant mouse, laggard.
  • organism-icon Mus musculus
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

We found a new spontaneous mutant mouse, laggard, characterized by general weakness in movements and retardation in growth.

Publication Title

Kif14 mutation causes severe brain malformation and hypomyelination.

Sample Metadata Fields

Specimen part

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accession-icon GSE52686
Expression data from mDCT cell-line over-expressing hMR
  • organism-icon Mus musculus
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Target gene of mineralocorticoid receptor (MR) is comparatively unknown, although distal convoluted tubule (DCT) expresses MR in in vivo.

Publication Title

Genome-wide analysis of murine renal distal convoluted tubular cells for the target genes of mineralocorticoid receptor.

Sample Metadata Fields

Cell line, Treatment

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accession-icon GSE145367
GeneChip Expression Array
  • organism-icon Rattus norvegicus
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Gene expression analysis to compare control cells and sorted cells

Publication Title

Identification of two major autoantigens negatively regulating endothelial activation in Takayasu arteritis.

Sample Metadata Fields

Specimen part

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accession-icon GSE25471
Expression profile in HEK293T cells transfected with control or ZAPS expression vector
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Analysis of HEK293T cells overexpressing ZAPS (zinc finger antiviral protein, short form; NP_078901), which is a member of the PARP (poly (ADP-ribose) polymerase)-superfamily. Results of gene profiles provide insight into the role of ZAPS in innate immunity.

Publication Title

ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses.

Sample Metadata Fields

Specimen part, Cell line

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accession-icon GSE56246
Dectin-1-mediated signaling leads to characteristic gene expressions in rat mast cells
  • organism-icon Rattus norvegicus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Rat Gene 1.0 ST Array (ragene10st)

Description

Rat mast cell line RBL-2H3 was analyzed to investigate the molecular mechanism of Dectin-1-mediated activation and responses of mast cells.

Publication Title

Dectin-1-mediated signaling leads to characteristic gene expressions and cytokine secretion via spleen tyrosine kinase (Syk) in rat mast cells.

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE50687
Expression data from testes of the mouse X-chromosome substitution strains
  • organism-icon Mus musculus
  • sample-icon 38 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

To investigate the evolutionary divergence of transcriptional regulation between the mouse subspecies, we performed transcriptome analysis by microarray on testes from the X-chromosome substitution strain, which carries different subspecies-derived X chromosome on the host subspecies genome. Transcription profiling showed that large-scale aberrations in gene expression were occurred on the introgressed X chromosome. This improper expression was restored by introducing chromosome 1 from the same donor strain as the X chromosome, suggesting that the genetic incompatibility between trans-acting regulatory gene(s) on chromosome 1 and X-linked downstream genes might be a cause of the misregulation.

Publication Title

Evolutionarily diverged regulation of X-chromosomal genes as a primal event in mouse reproductive isolation.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE5231
IGF1R Mediates Mammalian Immune Function in Response to FEZL
  • organism-icon Homo sapiens
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE5225
Expression data from OCUBM cells trasfected with IGF1R
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

To investigate genes that might influence resistance to infection through IGF1R, we screened human breast cancer-derived OCUB-M cells transfected with expression vector encoding IGF1R using microarray analysis.

Publication Title

Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE5224
Expression data from OCUBM cells trasfected with 12G FEZL
  • organism-icon Homo sapiens
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

To identify genes that influence resistance to mastitis, we scanned

Publication Title

Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.

Sample Metadata Fields

No sample metadata fields

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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