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accession-icon GSE22229
Identification of a B cell signature associated with renal transplant Tolerance in humans
  • organism-icon Homo sapiens
  • sample-icon 55 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

In this study, investigators recruited the largest reported cohort of tolerant kidney transplant recipients who maintained their graft after ceasing to take their immunosuppression drug, and compared this cohort to subjects with stable allograft function while on immunosuppression and healthy non transplated, controls. Using gene expression studies, they identified genetic markers that are strong candidates for predicting kidney transplant candidates who may benefit from minimization or withdrawl of immunosuppression.

Publication Title

Identification of a B cell signature associated with renal transplant tolerance in humans.

Sample Metadata Fields

Specimen part

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accession-icon GSE73464
Diagnosis of Kawasaki Disease in children using host RNA expression
  • organism-icon Homo sapiens
  • sample-icon 839 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V4.0 expression beadchip, Illumina HumanHT-12 V3.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Diagnosis of Kawasaki Disease Using a Minimal Whole-Blood Gene Expression Signature.

Sample Metadata Fields

Sex

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accession-icon GSE73461
Diagnosis of Kawasaki Disease in children using host RNA expression [Discovery_Dataset]
  • organism-icon Homo sapiens
  • sample-icon 459 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V3.0 expression beadchip, Illumina HumanHT-12 V4.0 expression beadchip

Description

Genome-wide analysis of transcriptional profiles in children <17 years of age with inflammatory diseases, bacterial or viral infections or with clinical features suggestive of infection.

Publication Title

Diagnosis of Kawasaki Disease Using a Minimal Whole-Blood Gene Expression Signature.

Sample Metadata Fields

Sex

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accession-icon GSE73463
Diagnosis of Kawasaki Disease in children using host RNA expression [Validation_HT12V4_Dataset]
  • organism-icon Homo sapiens
  • sample-icon 233 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V3.0 expression beadchip, Illumina HumanHT-12 V4.0 expression beadchip

Description

Genome-wide analysis of transcriptional profiles in children <17 years of age with inflammatory diseases, bacterial or viral infections or with clinical features suggestive of infection.

Publication Title

Diagnosis of Kawasaki Disease Using a Minimal Whole-Blood Gene Expression Signature.

Sample Metadata Fields

Sex

View Samples
accession-icon GSE73462
Diagnosis of Kawasaki Disease in children using host RNA expression [Validation_HT12V3_Dataset]
  • organism-icon Homo sapiens
  • sample-icon 147 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V3.0 expression beadchip

Description

Genome-wide analysis of transcriptional profiles in children <17 years of age with inflammatory diseases, bacterial or viral infections or with clinical features suggestive of infection.

Publication Title

Diagnosis of Kawasaki Disease Using a Minimal Whole-Blood Gene Expression Signature.

Sample Metadata Fields

Sex

View Samples
accession-icon GSE22470
Translocations Activating IRF4 Identify a Subtype of Germinal-Center-Derived B-cell Lymphoma Affecting Predominantly Children and Young Adults
  • organism-icon Homo sapiens
  • sample-icon 271 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

Background: Germinal center B-cell (GCB) lymphomas are common in children and adults. The prognosis strongly depends on age. Subgroups of GCB-lymphomas are characterized by chromosomal translocations affecting immunoglobulin (IG) loci leading to oncogene deregulation.

Publication Title

Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults.

Sample Metadata Fields

Sex, Age

View Samples
accession-icon GSE108113
Shared molecular targets in the glomerular and tubulointerstitial transcriptomes from patients with nephrotic syndrome and ANCA-associated vasculitis
  • organism-icon Homo sapiens
  • sample-icon 275 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 2.1 ST Array (hugene21st)

Description

This SuperSeries is composed of the SubSeries listed below. A subset of samples profiled in this analysis were also profiled in Series GSE68127, and GSE104066. Corresponding glomerular transcriptome data can be found under GEO ID: GSE108109.

Publication Title

Metabolic pathways and immunometabolism in rare kidney diseases.

Sample Metadata Fields

Specimen part

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accession-icon GSE104948
Glomerular Transcriptome from European Renal cDNA Bank subjects and living donors
  • organism-icon Homo sapiens
  • sample-icon 196 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

summary : Glomerular Transcriptome from European Renal cDNA Bank subjects and living donors. Samples included in this analysis have been previously analyzed using older CDF definitions and are included under previous GEO submissions - GSE47183 (chronic kidney disease samples), and GSE32591 (IgA nephropathy samples).

Publication Title

Metabolic pathways and immunometabolism in rare kidney diseases.

Sample Metadata Fields

Specimen part, Disease

View Samples
accession-icon GSE104954
Tubulointerstitial transcriptome from ERCB subjects with chronic kidney disease and living donor biopsies.
  • organism-icon Homo sapiens
  • sample-icon 194 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

summary : Tubulointerstitial transcriptome from ERCB subjects with chronic kidney disease and living donor biopsies. Samples included in this analysis have been previously analyzed using older CDF definitions and are included under previous GEO submissions - GSE47184 (chronic kidney disease samples), and GSE32591 (IgA nephropathy samples).

Publication Title

Metabolic pathways and immunometabolism in rare kidney diseases.

Sample Metadata Fields

Specimen part, Disease

View Samples
accession-icon GSE108112
Shared molecular targets in the tubulointerstitial transcriptome from patients with nephrotic syndrome and ANCA-associated vasculitis
  • organism-icon Homo sapiens
  • sample-icon 169 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 2.1 ST Array (hugene21st)

Description

Tubulointerstitial transcriptome from human kidney biopsies in Neptune and ERCB. A number of samples profiled in this analysis were also profiled in Series GSE68127.

Publication Title

Metabolic pathways and immunometabolism in rare kidney diseases.

Sample Metadata Fields

Specimen part

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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