This SuperSeries is composed of the SubSeries listed below.
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.
Age, Specimen part, Time
View SamplesPurpose: The goal of this study was to assess gene expression changes upon SAHA treatment in neurons derived from patients with A152T Tau mutation Overall design: iPSC derived neurons were treated with SAHA at different dosage for several days
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.
No sample metadata fields
View SamplesPurpose: The goal of this study was to assess gene expression changes upon SAHA treatment in cells overexpressing miR-203. Overall design: Primary cortical cultures were established using E15 cortical cultures from C57BL/6J mice. At DIV0, cells were infectd with either miR-203 (high titre - 1MOI) or intermediate titre (0.5MOI) or control (high 1MOI) lentivirus andalso treated with different dose of SAHA. At DIV8, total RNA was isolated using NucleoSpin RNA XS kit (Takara). Libraries were prepared using Standard illumina stranded mRNA-seq protocol.
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.
Specimen part, Subject
View SamplesThis study identifies a transciptomic myometrial profile associated with dystocia in spontanous nulliparous term labour
Identification of a myometrial molecular profile for dystocic labor.
Sex, Specimen part
View SamplesRNA sequencing data for four cell lines representing different stages during malignant transformation.
Majority of differentially expressed genes are down-regulated during malignant transformation in a four-stage model.
No sample metadata fields
View Samples