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accession-icon SRP099018
Single cell RNA expression of mouse embryonic basal forebrain
  • organism-icon Mus musculus
  • sample-icon 225 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Single-cell RNA-Seq RNA from medial ganglionic eminence at E11.5, E13.5, E15.5 or E17.5. The ID of this project in Genentech''s ExpressionPlot database is PRJ0007389 Overall design: Single-cell RNA-Seq from medial ganglionic eminence at E11.5, E13.5, E15.5 or E17.5.

Publication Title

Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types.

Sample Metadata Fields

Specimen part, Subject

View Samples
accession-icon SRP098938
Embryonic stem cells-derived neural progenitor cells
  • organism-icon Mus musculus
  • sample-icon 140 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

J14 ES cells differentiated into MGE-like cells. Three groups of single-cell preparations were analyzed: ES cells (undifferentiated), differentiated cells (unsorted, of which less than 10% are GFP+) and GFP+ differentiated cells. These are specified in the "group" sample characteristic, with values "ES", "Unsorted" and "GFP+" respectively. The "SAMPLE_ID" sample characteristic is a sample identifier internal to Genentech. The ID of this project in Genentech''s ExpressionPlot database is PRJ0007904 Overall design: J14 ES cells differentiated into MGE-like cells

Publication Title

Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types.

Sample Metadata Fields

Cell line, Subject

View Samples
accession-icon GSE13487
Antitumor efficacy of RAF inhibitor GDC-0879 involving BRAFV600E mutational status and ERK/MAPK pathway suppression
  • organism-icon Homo sapiens
  • sample-icon 30 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Unsupervised hierarchical clustering revealed a strong similarity in gene modulation resulting from either compound treatment or BRAF ablation mediated by RNA interference relative to DMSO-treated control samples .

Publication Title

Antitumor efficacy of the novel RAF inhibitor GDC-0879 is predicted by BRAFV600E mutational status and sustained extracellular signal-regulated kinase/mitogen-activated protein kinase pathway suppression.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE11103
Study of human immune and memory T cells using microarray
  • organism-icon Homo sapiens
  • sample-icon 39 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Deconvolution of blood microarray data identifies cellular activation patterns in systemic lupus erythematosus.

Sample Metadata Fields

Specimen part, Disease

View Samples
accession-icon GSE11057
Memory T Cell Subsets
  • organism-icon Homo sapiens
  • sample-icon 16 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Microarray deconvolution is a technique for quantifying the relative abundance of constituent cells in a mixture based on that mixture's microarray signature and the signatures of the purified constituents. It has been applied to yeast and other systems but not to blood samples.

Publication Title

Deconvolution of blood microarray data identifies cellular activation patterns in systemic lupus erythematosus.

Sample Metadata Fields

Specimen part, Disease

View Samples
accession-icon GSE11058
Immune Cell Line Mixtures
  • organism-icon Homo sapiens
  • sample-icon 16 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Microarray deconvolution is a technique for quantifying the relative abundance of constituent cells in a mixture based on that mixture's microarray signature and the signatures of the purified constituents. Its ability to discriminate related human cells is unknown.

Publication Title

Deconvolution of blood microarray data identifies cellular activation patterns in systemic lupus erythematosus.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE18377
Gene expression profiling of human DLBCL tumor samples (FF and FFPE pairs)
  • organism-icon Homo sapiens
  • sample-icon 35 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

We profiled human DLBCL tumor samples (FF and FFPE matched pairs) to identify the transcripts which are less prone to degradation in FFPE

Publication Title

CD40 pathway activation status predicts response to CD40 therapy in diffuse large B cell lymphoma.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE18376
Gene expression profiling of human DLBCL tumor samples (SGN-40 trial)
  • organism-icon Homo sapiens
  • sample-icon 23 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

We profiled human DLBCL patient samples to discover predictive biomarkers

Publication Title

CD40 pathway activation status predicts response to CD40 therapy in diffuse large B cell lymphoma.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE20585
The mutation spectrum revealed by paired genome sequences from a lung cancer patient
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

The mutation spectrum revealed by paired genome sequences from a lung cancer patient.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE20578
Assessment of mutation on expression levels
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

One lung tumor and its adjacent normal were profiled for expression levels with the Affymetrix HGU133 plus 2.0 array.

Publication Title

The mutation spectrum revealed by paired genome sequences from a lung cancer patient.

Sample Metadata Fields

Specimen part

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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