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Platform

accession-icon E-MTAB-2193
HEC1 transcriptional targets
  • organism-icon Arabidopsis thaliana
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Inflorescence apices of hec1,2,3 triple mutants and ethanol induced 35S:AlcR, AlcA:HEC1 plants were copared to wild-type or ethanol induced 35S:AlcR, AlcA:GUS apices, respectively.

Publication Title

A regulatory framework for shoot stem cell control

Sample Metadata Fields

Specimen part

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accession-icon SRP184773
Transcriptomic Comparison of the [SWI + ] Prion and SWI1 Deletion Effects in Yeast Saccharomyces cerevisiae
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 24 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

The aim of the project is to compare effects of Swi1 protein prionization and its deletional inactivation in Saccharomyces cerevisiae on transcriptomic level. All yeast samples were grown on solid MD media with galactose as a sole carbon source.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Disease, Cell line

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accession-icon GSE35917
Expression data of transduced mouse glioblastomas
  • organism-icon Mus musculus
  • sample-icon 30 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Description

Transgenic GFAP-, NES-, and SYN- CRE mice were injected with a lenti-viral construct containing a floxed RFP directly upstream of a cassette containing si-p53, GFP, and mutant HRAS. Tumors arising from the various CRE tissue specific promoters and differing injections sites were compared to normal hippocampus and cortex.

Publication Title

Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE30094
Analysis of the effect of auxin biosynthesis inhibitor L-AOPP on the gene expression profile
  • organism-icon Arabidopsis thaliana
  • sample-icon 24 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon GSE39210
Gene Expression of ESC and iPSC lines after specific differentiation
  • organism-icon Homo sapiens
  • sample-icon 18 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

We cultured hESC and hiPSC lines and compared the transcriptome of untreated cells with cells treated with Activin or BMP4 during 5 days

Publication Title

No associated publication

Sample Metadata Fields

Cell line

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accession-icon GSE36902
Linking Proteomic and Transcriptional Data through the Interactome and Epigenome Reveals a Map of Oncogene-induced Signaling
  • organism-icon Homo sapiens
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Linking proteomic and transcriptional data through the interactome and epigenome reveals a map of oncogene-induced signaling.

Sample Metadata Fields

Specimen part, Cell line

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accession-icon GSE30049
Expression data comparing the effect of IKK2 KO on a KRAS mouse model
  • organism-icon Mus musculus
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Description

Given that the NF-B pathway plays an important role in tumor development and that IKK2 is the seminal kinase responsible for NF-B pathway activation, we were particularly interested in exploring the therapeutic potential of IKK2 inhibition in non-small cell lung cancers.

Publication Title

Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE30093
Analysis of the effect of auxin biosynthesis inhibitor L-AOPP on the gene expression profile (whole plant)
  • organism-icon Arabidopsis thaliana
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Recently, 2-aminoxy-3-phenylpropionic acid (L-AOPP) had been demonstrated to possess an inhibitory activity against IAA biosynthesis but the molecular basis of the action was unclear. To investigate the function of L-AOPP in relation to Auxin biosynthesis, we conducted microarray analysis.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE30092
Analysis of the effect of auxin biosynthesis inhibitor L-AOPP on the gene expression profile (shoot apical meristem)
  • organism-icon Arabidopsis thaliana
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Recently, 2-aminoxy-3-phenylpropionic acid (L-AOPP) had been demonstrated to possess an inhibitory activity against IAA biosynthesis but the molecular basis of the action was unclear. To investigate the function of L-AOPP, we conducted microarray analysis using the shoot apical meristem (SAM) part of A. thaliana in addition to whole plants after the treatment of L-AOPP.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE25513
AMPK and calcineurin induced longevity is mediated by CRTC-1 and CREB
  • organism-icon Caenorhabditis elegans
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix C. elegans Genome Array (celegans)

Description

AMPK (AAK-2) and calcineurin (TAX-6) mediate longevity exclusively through post-translational modification of CRTC-1, the sole C. elegans CRTC (CREB regulated transcriptional coactivator).

Publication Title

Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB.

Sample Metadata Fields

No sample metadata fields

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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