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accession-icon GSE101941
Gene expression analysis of c-Myc overexpressing human fibroblasts.
  • organism-icon Homo sapiens
  • sample-icon 1 Downloadable Sample
  • Technology Badge Icon Affymetrix Human Gene 2.0 ST Array (hugene20st)

Description

Analysis of gene expression change of normal cells, human fore skin fibroblast (HFFs) upon over-expression of c-Myc

Publication Title

Oncogene-induced senescence mediated by c-Myc requires USP10 dependent deubiquitination and stabilization of p14ARF.

Sample Metadata Fields

Cell line

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accession-icon GSE16170
Genome-wide analysis of miRNA-targeted cellular NMD substrates in HeLa cell
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconIllumina HumanRef-8 v3.0 expression beadchip

Description

Analysis of miRNA-targeted cellular NMD substrates in HeLa cell. The hypothesis tested in the present study was that endogenous NMD substrates containing long 3' untranslated region may targeted for miRNA. Results provide important information expanding the roles of miRISC in the posttranscriptional regulation of gene expression: a new cross-talk between miRNA-mediated gene silencing and NMD.

Publication Title

microRNA/Argonaute 2 regulates nonsense-mediated messenger RNA decay.

Sample Metadata Fields

No sample metadata fields

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accession-icon SRP081188
Homo sapiens Transcriptome or Gene expression
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 4000

Description

human Transcriptomehuman Transcriptomehuman Transcriptomehuman Transcriptomehuman Transcriptome

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part

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accession-icon SRP106521
Transcriptome Analysis of Male Drosophila melanogaster Exposed to Ethylparaben
  • organism-icon Drosophila melanogaster
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 4000

Description

This study revealed the EP impact on gene expression in fruit fly and provided new insight into the mechanisms of this response, which is helpful for understanding EP toxicity to humans.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part

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accession-icon SRP150561
RNA-seq of human gastric cancer cell line (AGS)
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 4000

Description

Transcriptomic sequencing of human gastric cancer cell line (AGS) upon citral treatment

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Disease, Cell line

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accession-icon SRP093910
sequencing of Arabidopsis wild-type and TabZIP60s overexpression lines before and after heat stress
  • organism-icon Arabidopsis thaliana
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

It has been reported that IRE1-bZIP60 pathway is conserved for the signal transduction and gene regulation in response to ER stress including high temperature among human, yeast, Arabidopsis, rice and maize. However, the information of their counterparts in wheat is limited and, especially, the biological relevance of the equivalent pathway contributing to heat tolerance is still ambiguous. In present study, we identified heat stress-induced wheat bZIP60 and investigated its splicing pattern depending on IRE1.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Treatment

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accession-icon SRP116227
Transcriptome analysis of maize immature embryos reveals the roles of cysteine in improving Agrobacterium infection efficiency
  • organism-icon Zea mays
  • sample-icon 1 Downloadable Sample
  • Technology Badge IconIllumina HiSeq 2500

Description

In this study, the immature embyros of inbred line Z31and hybrid HiII were heated in 45 ?C water bath for 2 min, and then infected with Agrobacterium suspension for 5 min. After infection, the immature embryos were transferred onto CO-medium with or without 100 mg L-1 cysteine which is freshly prepared and filter-sterilized. After culturing for 3 days at 25 ?C under dark conditions, the immature embryos were collected, and stored at -70 ?C for RNA extraction. The genes up-regulated and down regulated both in Z31 and HiII were analyzed, and elucidate the role of cysteine in improving the efficiency of Agrobacterium infection of maize immature embryo, and provide important information for the improvement of the maize transformation.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon SRP116239
Transcriptome analysis of maize immature embryos reveals the roles of cysteine in improving Agrobacterium infection efficiency(HiII 1-2)
  • organism-icon Zea mays
  • sample-icon 1 Downloadable Sample
  • Technology Badge IconIllumina HiSeq 2000

Description

In this study, the immature embyros of inbred line Z31and hybrid HiII were heated in 45 C water bath for 2 min, and then infected with Agrobacterium suspension for 5 min. After infection, the immature embryos were transferred onto CO-medium with or without 100 mg L-1 cysteine which is freshly prepared and filter-sterilized. After culturing for 3 days at 25 C under dark conditions, the immature embryos were collected, and stored at -70 C for RNA extraction. The genes up-regulated and down regulated both in Z31 and HiII were analyzed, and elucidate the role of cysteine in improving the efficiency of Agrobacterium infection of maize immature embryo, and provide important information for the improvement of the maize transformation.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

View Samples
accession-icon SRP116247
Transcriptome analysis of maize immature embryos reveals the roles of cysteine in improving Agrobacterium infection efficiency(HiII 2-4)
  • organism-icon Zea mays
  • sample-icon 1 Downloadable Sample
  • Technology Badge IconIllumina HiSeq 2000

Description

In this study, the immature embyros of inbred line Z31and hybrid HiII were heated in 45 C water bath for 2 min, and then infected with Agrobacterium suspension for 5 min. After infection, the immature embryos were transferred onto CO-medium with or without 100 mg L-1 cysteine which is freshly prepared and filter-sterilized. After culturing for 3 days at 25 C under dark conditions, the immature embryos were collected, and stored at -70 C for RNA extraction. The genes up-regulated and down regulated both in Z31 and HiII were analyzed, and elucidate the role of cysteine in improving the efficiency of Agrobacterium infection of maize immature embryo, and provide important information for the improvement of the maize transformation.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

View Samples
accession-icon SRP116241
Transcriptome analysis of maize immature embryos reveals the roles of cysteine in improving Agrobacterium infection efficiency(HiII 2-1)
  • organism-icon Zea mays
  • sample-icon 1 Downloadable Sample
  • Technology Badge IconIllumina HiSeq 2000

Description

In this study, the immature embyros of inbred line Z31and hybrid HiII were heated in 45 C water bath for 2 min, and then infected with Agrobacterium suspension for 5 min. After infection, the immature embryos were transferred onto CO-medium with or without 100 mg L-1 cysteine which is freshly prepared and filter-sterilized. After culturing for 3 days at 25 C under dark conditions, the immature embryos were collected, and stored at -70 C for RNA extraction. The genes up-regulated and down regulated both in Z31 and HiII were analyzed, and elucidate the role of cysteine in improving the efficiency of Agrobacterium infection of maize immature embryo, and provide important information for the improvement of the maize transformation.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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